是構(gòu)成遺傳的基本單位；編碼蛋白所有信息的DNA序列。從結(jié)構(gòu)上來(lái)講，基因包含三個(gè)區(qū)域：稱為啟動(dòng)子的調(diào)節(jié)區(qū)域；與其并列的編碼蛋白質(zhì)的密碼子區(qū)域；以及3'端尾部序列。在哺乳動(dòng)物細(xì)胞里，啟動(dòng)子是一個(gè)包含著許多蛋白質(zhì)結(jié)合位點(diǎn)的復(fù)雜區(qū)域，它調(diào)節(jié)基因的表達(dá)。單個(gè)基因可以被激活，由這些控制蛋白決定時(shí)間、地點(diǎn)及蛋白表達(dá)量，從而產(chǎn)生蛋白質(zhì)。這一過(guò)程稱為基因表達(dá)。在人類基因組中，大約有10萬(wàn)個(gè)基因。其中一些進(jìn)化過(guò)程相關(guān)聯(lián)而形成 "基因家族"表達(dá)相關(guān)蛋白。也有基因不再制造蛋白，這些進(jìn)化中的殘余物稱為假基因。

The basic unit of heredity; the sequence of DNA that encodes all the information to make a protein. Structurally, a gene is formed by three regions: a regulatory region called the promoter juxtaposed to the coding region containing the protein sequence, and a “3’ tail” sequence. In mammalian cells, the promoter is a complex region containing binding sites for many proteins that regulate gene expression. A gene may be “activated” or “switched on” to make protein – this activation is referred to as gene expression - by these proteins which control when, where and how much protein is expressed from the gene. In the human genome, there are an estimated 100,000 genes. Some of these are evolutionarily related and form“gene families” that express related proteins. There are also genes that no longer make a protein; these defective remnants of evolution are called pseudogenes.